Australasian Journal of Dermatology provides the latest peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology.

Featured Article

An individual patient data meta-analysis of wound care in patients with toxic epidermal necrolysis

Lee, J.S. Mallitt, K. Fischer, G. Saunderson, R.B.

Toxic epidermal necrolysis (TEN) involves extensive mucocutaneous loss and care is supportive. The approach to wound care involves surgical debridement or using dressings while leaving the epidermis intact. As scientific evidence for either approach is limited, a systematic review and meta-analysis was undertaken to determine whether surgical debridement compared to dressings while leaving the epidermis in situ will lead to a mortality benefit in adult patients with TEN.

A total of 54 studies involving 227 patients were included in the study, with a GRADE score from very low to moderate. Findings suggest that there was no significant difference in survival in patients who had surgical debridement or dressings. Patients treated with dressings experienced faster re-epithelialization (multivariate HR: 1.96 [1.09–3.51], p = 0.023). Intravenous immunoglobulin (p<0.001) and cyclosporin (p=0.046) significantly reduced mortality, regardless of the wound care method.

This study supports the expert consensus of the dermatology hospitalists that wound care in patients with TEN should be supportive with the epidermis left intact and supported with dressings, leading to faster re-epithelialization.

About the Journal

The Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society. Editorially independent and peer-reviewed, the journal showcases the latest in dermatology research and innovation.

With four issues a year and special editions, the journal covers clinical presentations, medical and physical therapies and investigations, including dermatopathology, mycology, dermoscopy, surgery and contact dermatitis.

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Editorial Board


Associate Professor John Frew

University of New South Wales, Sydney, Australia

Dr Harriet Kennedy

Auckland City Hospital, Auckland, New Zealand

A/Prof Frew is a clinical dermatologist and Director of Research at The Skin Hospital in Sydney, Australia. 

He is a Conjoint A/Prof of Dermatology at the University of New South Wales and is the current Editor-in-Chief of the Australasian Journal of Dermatology. 

He currently holds a clinical appointment at Liverpool Hospital in Sydney, Australia and is Head of the Laboratory of Translational Cutaneous Medicine at the Ingham Institute for Applied Medical Research. 

A/Prof has authored over 130 peer-reviewed articles and has a special interest in pathogenesis and molecular mechanisms of inflammatory dermatoses.


Dr Kennedy is a dermatologist at Auckland City Hospital in New Zealand. 

She is a general dermatologist with special interests in patch testing and vulval dermatology, and she has a masters degree in contact allergy from the University of Sydney. 

Dr Kennedy is a honorary Senior Lecturer at the University of Auckland and has been on the Editorial Board of the Australasian Journal of Dermatology since 2018. 

Dr Nikki AdlerMonash University, Melbourne, Australia
Dr Bruno BlayaThe Skin Hospital, Sydney, Australia
Dr Peggy ChenTaranaki District Health Board, New Plymouth, New Zealand
Dr Karen CheungThe Skin Hospital, Sydney, Australia
Dr Shih-Sung CheungChi Mei Medical Centre, Tainan, Taiwan
Dr Helena Collgros TotosausNew South Wales Health, Australia
Dr Gyohei EgawaKyoto University, Kyoto, Japan
Dr Haady FallahConcord Repatriation General Hospital, Sydney, Australia
Prof Pablo Fernandez-PenasUniversity of Sydney, Sydney, Australia
Dr Bryan E.K. GuevaraSouthern Philippines Medical Centre, Davao, Philippines
Dr Monisha GuptaThe Skin Hospital, Sydney, Australia
Dr Izolda HydenrychCosmetic Dermatology Centre, Cape Town, South Africa
Prof Johannes KernSkin Health Institute, Melbourne, Australia
Prof Kiarash KhosrotehraniInstitute for Molecular Bioscience, The University of Queensland Diamantina Institute, Brisbane Australia
Dr Joseph KonyaThe Skin Hospital, Sydney, Australia
A/Prof Christopher McCormackPeter MacCallum Cancer Centre, Melbourne, Australia
Dr Gilberto Moreno BonillaThe Skin Hospital, Sydney, Australia
Dr Je-Ho MunSeoul National University, Seoul, South Korea
Dr Dany NassarHospital Cochin, Paris, France
A/Prof David OrchardPrivate Suites Royal Children’s Hospital, Melbourne, Australia
Dr Yan PanVictorian Melanoma Service, Alfred Hospital, Victoria, Australia
Dr Julio Cesar Salas-AlanisSchool of Medicine and Health Services TecSalud ITESM, Mexico
A/Prof Stephen ShumackRoyal North Shore Hospital of Sydney, Sydney, Australia
A/Prof Deshan SebaratnamUniversity of New South Wales, Sydney, Australia
A/Prof Helmut SchaiderDermatology Research Centre, The University of Queensland Diamantina Institute, Brisbane, Australia
Prof Rodney SinclairUniversity of Melbourne and Epworth Hospital, Melbourne, Australia
Prof H Peter SoyerDermatology Research Centre, The University of Queensland Diamantina Institute, Brisbane, Australia
Dr Artiene TatianSydney Children’s Hospital, Sydney, Australia
A/Prof Steven ThngSkin Research Institute of Singapore, Singapore
Prof Maurice van SteenselInstitute of Medical Biology, Singapore
Dr Etienne WangNational Skin Centre, Singapore
Prof Orli WargonSydney Children’s Hospital, Sydney, Australia
Dr Belinda WelshComplete Skin Specialists, Sunbury, Victoria, Australia
Prof Chao-Chun YangNational Cheng Kung University, Tainan City, Taiwan
Dr Ashfaq Marghoob Memorial Sloan Kettering Skin Cancer Center, New York, NY, USA
Prof John McGrath St John’s Institute of Dermatology, London, United Kingdom
Dr Masaru Tanaka Tokyo Woman’s Medical University, Medical Center East, Tokyo, Japan
Dr Mark Tang National Skin Centre, Singapore
Dr Clark C Otley Mayo Clinic, Rochester, USA

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